The democratization of protein design now enables the rapid generation of new functional proteins using a simple laptop. In this talk, I will briefly discuss recent developments in the field of ML-based protein design. We will then explore some of the open-source and API-based models available online and demonstrate how they can be used at home. Using beer production as a case study, we will explore how these open-source models can be applied to hack fermentation yeast, to brew better, more nutritious beer.